Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever.

Lassa fever (LASF) is a highly severe viral syndrome endemic to West African countries. Despite the annual high morbidity and mortality caused by LASF, very little is known about the pathophysiology of the disease. Basic research on LASF has been precluded due to the lack of relevant small animal mo...

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Bibliographic Details
Main Authors: Lisa Oestereich, Anja Lüdtke, Paula Ruibal, Elisa Pallasch, Romy Kerber, Toni Rieger, Stephanie Wurr, Sabrina Bockholt, José V Pérez-Girón, Susanne Krasemann, Stephan Günther, César Muñoz-Fontela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005656