Fallacy of the Unique Genome: Sequence Diversity within Single Helicobacter pylori Strains
Many bacterial genomes are highly variable but nonetheless are typically published as a single assembled genome. Experiments tracking bacterial genome evolution have not looked at the variation present at a given point in time. Here, we analyzed the mouse-passaged Helicobacter pylori strain SS1 and...
Main Authors: | Jenny L. Draper, Lori M. Hansen, David L. Bernick, Samar Abedrabbo, Jason G. Underwood, Nguyet Kong, Bihua C. Huang, Allison M. Weis, Bart C. Weimer, Arnoud H. M. van Vliet, Nader Pourmand, Jay V. Solnick, Kevin Karplus, Karen M. Ottemann, Claire M. Fraser |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-02-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/1/e02321-16 |
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