Rad50 mediates DNA demethylation to establish pluripotent reprogramming

Regenerative medicine: Protein boosts stem cell generation process Heightened expression of a DNA repair protein improves efficiency when generating induced pluripotent stem cells (iPSCs) for use in regenerative medicine. DNA demethylation – the removal of methyl groups from one of the DNA bases, cy...

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Bibliographic Details
Main Authors: Hanseul Park, Byounggook Cho, Jongpil Kim
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0467-0