Adherence as a predictor of the development of class-specific resistance mutations: the Swiss HIV Cohort Study.

BACKGROUND:Non-adherence is one of the strongest predictors of therapeutic failure in HIV-positive patients. Virologic failure with subsequent emergence of resistance reduces future treatment options and long-term clinical success. METHODS:Prospective observational cohort study including patients st...

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Main Authors: Viktor von Wyl, Thomas Klimkait, Sabine Yerly, Dunja Nicca, Hansjakob Furrer, Matthias Cavassini, Alexandra Calmy, Enos Bernasconi, Jürg Böni, Vincent Aubert, Huldrych F Günthard, Heiner C Bucher, Tracy R Glass, Swiss HIV Cohort Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3797701?pdf=render