Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10

Summary: Siglec-10 is an inhibitory I-type lectin selectively recognizing sialoglycans exposed on cell surfaces, involved in several patho-physiological processes. The key role Siglec-10 plays in the regulation of immune cell functions has made it a potential target for the development of immunother...

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Bibliographic Details
Main Authors: Rosa Ester Forgione, Cristina Di Carluccio, Juan Guzmán-Caldentey, Rosa Gaglione, Filomena Battista, Fabrizio Chiodo, Yoshiyuki Manabe, Angela Arciello, Pompea Del Vecchio, Koichi Fukase, Antonio Molinaro, Sonsoles Martín-Santamaría, Paul R. Crocker, Roberta Marchetti, Alba Silipo
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304168