Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report

Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This r...

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Main Authors: Saede Atarbashi-Moghadam, Ali Lotfi, Shokoufeh Shahrabi-Farahani, Fazele Atarbashi-Moghadam
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2018-06-01
Series:Journal of Dentistry
Subjects:
Online Access:http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1696/1125
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spelling doaj-2fd6057ac8774afd897ec9196d7c9ad82020-11-24T22:07:19ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182018-06-01192164167Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case ReportSaede Atarbashi-Moghadam 0Ali Lotfi 1Shokoufeh Shahrabi-Farahani 2Fazele Atarbashi-Moghadam 3Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Division of Oral and Maxillofacial Pathology, Dept. of Diagnostic Sciences and Oral Medicine, University of Tennessee Health Science Center, College of Dentistry, Memphis, TN.Dept. of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This report presents a 4-year-old male patient with a rapidly growing mandibular gingival mass with some evidence of underlying alveolar bone destruction. Incisional biopsy was performed and the specimen was stained with hematoxylin and eosin and immunohistochemical antibodies for αSMA, CD34, S100 and desmin. The diagnosis of myofibroma was made and the lesion was completely excised. The knowledge about microscopic features of this rare neoplasm helps to have a proper diagnosis and avoid unnecessary treatment.http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1696/1125MyofibromaSmooth Muscle ActinGingivaImmunohistochemistrySoft Tissue Neoplasms
collection DOAJ
language English
format Article
sources DOAJ
author Saede Atarbashi-Moghadam
Ali Lotfi
Shokoufeh Shahrabi-Farahani
Fazele Atarbashi-Moghadam
spellingShingle Saede Atarbashi-Moghadam
Ali Lotfi
Shokoufeh Shahrabi-Farahani
Fazele Atarbashi-Moghadam
Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
Journal of Dentistry
Myofibroma
Smooth Muscle Actin
Gingiva
Immunohistochemistry
Soft Tissue Neoplasms
author_facet Saede Atarbashi-Moghadam
Ali Lotfi
Shokoufeh Shahrabi-Farahani
Fazele Atarbashi-Moghadam
author_sort Saede Atarbashi-Moghadam
title Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
title_short Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
title_full Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
title_fullStr Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
title_full_unstemmed Myofibroma as a Rapidly Growing Gingival Mass in a 4-year-old Boy: a Case Report
title_sort myofibroma as a rapidly growing gingival mass in a 4-year-old boy: a case report
publisher Shiraz University of Medical Sciences
series Journal of Dentistry
issn 2345-6485
2345-6418
publishDate 2018-06-01
description Solitary myofibroma is an uncommon benign soft tissue neoplasm of myofibroblastic origin exhibiting head and neck region predilection but its presence in the jaws is rare. Myofibroma presents as painless mass and may demonstrate rapid enlargement and growth that clinically mimic malignancies. This report presents a 4-year-old male patient with a rapidly growing mandibular gingival mass with some evidence of underlying alveolar bone destruction. Incisional biopsy was performed and the specimen was stained with hematoxylin and eosin and immunohistochemical antibodies for αSMA, CD34, S100 and desmin. The diagnosis of myofibroma was made and the lesion was completely excised. The knowledge about microscopic features of this rare neoplasm helps to have a proper diagnosis and avoid unnecessary treatment.
topic Myofibroma
Smooth Muscle Actin
Gingiva
Immunohistochemistry
Soft Tissue Neoplasms
url http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1696/1125
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