Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against <i>Streptococcus mutans</i> with Reduced Hemolysis

In our previous study, temporin-GHaR (GHaR) showed potent antimicrobial activity with strong hemolytic toxicity. To overcome its weakness, we designed GHaR6R, GHaR7R, GHaR8R, GHaR9R, and GHaR9W by changing the number of positive charges and the hydrophobic surface of GHaR. With the exception of GHaR...

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Bibliographic Details
Main Authors: Hanqi Wei, Zhipeng Xie, Xiuchuan Tan, Ran Guo, Yanting Song, Xi Xie, Rong Wang, Lushuang Li, Manchuriga Wang, Yingxia Zhang
Format: Article
Published: MDPI AG 2020-12-01
Online Access:https://www.mdpi.com/1420-3049/25/23/5724