Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: Effects of antipsychotic drugs

Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: Effects of antipsychotic drugs

Recent animal and human studies have suggested that the cuprizone (CPZ, a copper chelator)-feeding C57BL/6 mouse may be used as an animal model of schizophrenia. The goals of this study were to see the recovery processes of CPZ-induced behavioral changes and damaged white matter and to examine possi...

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Bibliographic Details
Main Authors: Haiyun eXu, Hong-Ju eYang, Gregory M Rose, Xin-Min eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Behavior
Cuprizone
Schizophrenia
myelin
oligodendrocytes
antipsychotic drugs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00031/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00031/full

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