Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy

Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy

Diabetic retinopathy (DR) is a frequent diabetes-associated complication. Pericyte dropout can cause increased vascular permeability and contribute to vascular occlusion. Adipose-derived stromal cells (ASC) have been suggested to replace pericytes and restore microvascular support as potential thera...

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Bibliographic Details
Main Authors: Heiner Kremer, Julian Gebauer, Susanne Elvers-Hornung, Stefanie Uhlig, Hans-Peter Hammes, Elena Beltramo, Lothar Steeb, Martin C. Harmsen, Carsten Sticht, Harald Klueter, Karen Bieback, Agnese Fiori
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human adipose-derived stromal cells
human retinal pericytes
diabetic retinopathy
angiogenesis
vascular–endothelial growth factor
angiopoietin
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00387/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00387/full

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