NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy

NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure, and the underlying mechanism remains largely elusive. Here we investigated whether NLRP3 inflammasome-mediated pyroptosis contributes to non-ischemic DCM and dissected the underlying mechanism. We found that hyper activa...

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Bibliographic Details
Main Authors: Cheng Zeng, Fengqi Duan, Jia Hu, Bin Luo, Binlong Huang, Xiaoying Lou, Xiuting Sun, Hongyu Li, Xuanhong Zhang, Shengli Yin, Hongmei Tan
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Dilated cardiomyopathy
Heart failure
NOX
NLRP3 inflammasome
Pyroptosis
Mitochondrial fission
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172030286X

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http://www.sciencedirect.com/science/article/pii/S221323172030286X

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