Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation

Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation

Acute lung injury (ALI) which is featured by a strong pulmonary inflammation, is a major cause of morbidity and mortality in critically ill patients. Magnoflorine, a quaternary alkaloid isolated from Chinese herb Magnolia or Aristolochia, has been reported to have potent anti-inflammatory properties...

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Bibliographic Details
Main Authors: Shuai Guo, Kangfeng Jiang, Haichong Wu, Chao Yang, Yaping Yang, Jing Yang, Gan Zhao, Ganzhen Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
magnoflorine
anti-inflammation
ALI
LPS
NF-κB
MAPK
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00982/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00982/full

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