Uncertainty quantification of parenchymal tracer distribution using random diffusion and convective velocity fields

Abstract Background Influx and clearance of substances in the brain parenchyma occur by a combination of diffusion and convection, but the relative importance of these mechanisms is unclear. Accurate modeling of tracer distributions in the brain relies on parameters that are partially unknown and wi...

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Bibliographic Details
Main Authors: Matteo Croci, Vegard Vinje, Marie E. Rognes
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12987-019-0152-7