Serum cystatin C as a marker of glomerular kidney damage in patients with chronic glomerulonephritis with saved renal function

• Main Authors: O. V. Kraydashenko, M. A. Dolinna
• Format: Article
• Language: English
• Published: Zaporozhye State Medical University 2015-06-01
• Series: Zaporožskij Medicinskij Žurnal
• Subjects: Glomerulonephritis; Glomerular; Cystatin C
• Online Access: http://zmj.zsmu.edu.ua/article/view/44455/42738

Improving of glomerular damage diagnostics in chronic glomerulonephritis (CGN) is an actual theme. Aim. To analyze indicators of glomerular kidney damage in CGN patients. Methods and results. We examined 81 patients with CGN and saved renal function to analyze indicators of glomerular kidney damage according to vivo morphological kidney study in CGN patients with and without arterial hypertension (AH) and relationship between serum cystatin C (CysC) and histological parameters. Conclusion. Patients with hypertension had more expressed indicators of glomerular damage than patients without hypertension. We demonstrated that serum cysC is a marker of glomerular kidney damage in patients with CGN.