Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016
Background: Primary immunodeficiencies are inherited diseases that compromise numerous systems and whose clinical manifestation is varied. It is an underdiagnosed pathology in Colombia. Objectives: To characterize primary immunodeficiencies in patients younger than 16 years who attended the San Raf...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | Spanish |
Published: |
Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2018-12-01
|
Series: | Revista Alergia México |
Subjects: | |
Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/338 |
id |
doaj-313671f298c54d0e82e0b2940d366857 |
---|---|
record_format |
Article |
spelling |
doaj-313671f298c54d0e82e0b2940d3668572020-11-25T03:51:40ZspaColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902018-12-0165434134810.29262/ram.v65i4.338379Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016Ángela Pedraza0María Isabel Vargas-Rumilla1Juan Leandro Ramírez-Roa2Hospital Universitario Clínica San Rafael, BogotáHospital Universitario Clínica San Rafael, BogotáHospital Universitario Clínica San Rafael, BogotáBackground: Primary immunodeficiencies are inherited diseases that compromise numerous systems and whose clinical manifestation is varied. It is an underdiagnosed pathology in Colombia. Objectives: To characterize primary immunodeficiencies in patients younger than 16 years who attended the San Rafael Clinical University Hospital, Bogota, between January 1, 2010 and July 1, 2016, as well as to provide information that enriches local, national and international statistics. Methods: Observational study of a cases series. All patients diagnosed with primary immunodeficiencies were analyzed, with a total of 75 patients. Results: Patients between one and five years of age (33 % of all cases) were the most affected, followed by patients from six to 11 months, including 17 cases; 21 cases corresponded to patients under 1 year of age; 80 % of affected children were males. Antibody deficiency was the most common type of immunodeficiency (56 %), followed by T/B lymphocyte deficiency (38 %). Conclusions: Patients with primary immunodeficiencies of the analyzed hospital had the same age and gender distribution observed in international studies. The most common primary immunodeficiency was due to antibody defects.http://revistaalergia.mx/ojs/index.php/ram/article/view/338inmunodeficiencia primariasusceptibilidad inmunológicasubdiagnóstico |
collection |
DOAJ |
language |
Spanish |
format |
Article |
sources |
DOAJ |
author |
Ángela Pedraza María Isabel Vargas-Rumilla Juan Leandro Ramírez-Roa |
spellingShingle |
Ángela Pedraza María Isabel Vargas-Rumilla Juan Leandro Ramírez-Roa Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016 Revista Alergia México inmunodeficiencia primaria susceptibilidad inmunológica subdiagnóstico |
author_facet |
Ángela Pedraza María Isabel Vargas-Rumilla Juan Leandro Ramírez-Roa |
author_sort |
Ángela Pedraza |
title |
Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016 |
title_short |
Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016 |
title_full |
Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016 |
title_fullStr |
Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016 |
title_full_unstemmed |
Registry of primary immunodeficiencies in children at a fourth level hospital. Bogota, 2010-2016 |
title_sort |
registry of primary immunodeficiencies in children at a fourth level hospital. bogota, 2010-2016 |
publisher |
Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
series |
Revista Alergia México |
issn |
0002-5151 2448-9190 |
publishDate |
2018-12-01 |
description |
Background: Primary immunodeficiencies are inherited diseases that compromise numerous systems and whose clinical manifestation is varied. It is an underdiagnosed pathology in Colombia.
Objectives: To characterize primary immunodeficiencies in patients younger than 16 years who attended the San Rafael Clinical University Hospital, Bogota, between January 1, 2010 and July 1, 2016, as well as to provide information that enriches local, national and international statistics.
Methods: Observational study of a cases series. All patients diagnosed with primary immunodeficiencies were analyzed, with a total of 75 patients.
Results: Patients between one and five years of age (33 % of all cases) were the most affected, followed by patients from six to 11 months, including 17 cases; 21 cases corresponded to patients under 1 year of age; 80 % of affected children were males. Antibody deficiency was the most common type of immunodeficiency (56 %), followed by T/B lymphocyte deficiency (38 %).
Conclusions: Patients with primary immunodeficiencies of the analyzed hospital had the same age and gender distribution observed in international studies. The most common primary immunodeficiency was due to antibody defects. |
topic |
inmunodeficiencia primaria susceptibilidad inmunológica subdiagnóstico |
url |
http://revistaalergia.mx/ojs/index.php/ram/article/view/338 |
work_keys_str_mv |
AT angelapedraza registryofprimaryimmunodeficienciesinchildrenatafourthlevelhospitalbogota20102016 AT mariaisabelvargasrumilla registryofprimaryimmunodeficienciesinchildrenatafourthlevelhospitalbogota20102016 AT juanleandroramirezroa registryofprimaryimmunodeficienciesinchildrenatafourthlevelhospitalbogota20102016 |
_version_ |
1724486259279134720 |