Immunological discrimination between the human apolipoprotein E2(Arg158—-Cys) and E3 isoforms.
A specific anti-apoE2(Arg158—-Cys) monoclonal antibody was raised by means of immunization of mice with a variant specific synthetic peptide. The peptide sequences used were homologous to apolipoprotein E of human and mouse. Consequently, the mouse immune system was tolerant to most of the selected...
Main Authors: | K Gerritse, P de Knijff, G van Ierssel, LM Havekes, RR Frants, MM Schellekens, N D Zegers, E Claassen, WJ Boersma |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1992-02-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520415470 |
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