Circulating Long Non-Coding RNA GAS5 Is Overexpressed in Serum from Osteoporotic Patients and Is Associated with Increased Risk of Bone Fragility

Circulating Long Non-Coding RNA GAS5 Is Overexpressed in Serum from Osteoporotic Patients and Is Associated with Increased Risk of Bone Fragility

Osteoporosis (OP) is a multifactorial disorder in which environmental factors along with genetic variants and epigenetic mechanisms have been implicated. Long non-coding RNAs (lncRNAs) have recently emerged as important regulators of bone metabolism and OP aetiology. In this study, we analyzed the e...

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Bibliographic Details
Main Authors: Virginia Veronica Visconti, Simona Fittipaldi, Simone Ciuffi, Francesca Marini, Giancarlo Isaia, Patrizia D’Amelio, Silvia Migliaccio, Claudio Marcocci, Salvatore Minisola, Ranuccio Nuti, Giuseppe Novelli, Maria Luisa Brandi, Annalisa Botta, Umberto Tarantino
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
osteoporosis
biomarker
epigenetics
lncRNA GAS5
bone fragility
Online Access:https://www.mdpi.com/1422-0067/21/18/6930

Internet

https://www.mdpi.com/1422-0067/21/18/6930

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