Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats

Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats

Gut microbiota produces a wide and diverse array of metabolites that are an integral part of the host metabolome. The emergence of the gut microbiome-brain axis concept has prompted investigations on the role of gut microbiota dysbioses in the pathophysiology of brain diseases. Specifically, the sea...

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Bibliographic Details
Main Authors: Mathilde Jaglin, Moez Rhimi, Catherine Philippe, Nicolas Pons, Aurélia Bruneau, Bénédicte Goustard, Valérie Daugé, Emmanuelle Maguin, Laurent Naudon, Sylvie Rabot
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Neuroscience
Subjects:
microbiota
tryptophanase
indole
oxindoles
vagus nerve
behavior
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2018.00216/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2018.00216/full

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