A role for Na+,K+-ATPase α1 in regulating Rab27a localisation on melanosomes.

The mechanism(s) by which Rab GTPases are specifically recruited to distinct intracellular membranes remains elusive. Here we used Rab27a localisation onto melanosomes as a model to investigate Rab targeting. We identified the α1 subunit of Na+,K+-ATPase (ATP1a1) as a novel Rab27a interacting protei...

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Bibliographic Details
Main Authors: Antonia E G Booth, Abul K Tarafder, Alistair N Hume, Chiara Recchi, Miguel C Seabra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4106853?pdf=render