Long Noncoding RNA MEG3 Interacts with p53 Protein and Regulates Partial p53 Target Genes in Hepatoma Cells.

Maternally Expressed Gene 3 (MEG3) encodes a lncRNA which is suggested to function as a tumor suppressor. Previous studies suggested that MEG3 functioned through activation of p53, however, the functional properties of MEG3 remain obscure and their relevance to human diseases is under continuous inv...

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Bibliographic Details
Main Authors: Juanjuan Zhu, Shanshan Liu, Fuqiang Ye, Yuan Shen, Yi Tie, Jie Zhu, Lixin Wei, Yinghua Jin, Hanjiang Fu, Yongge Wu, Xiaofei Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4596861?pdf=render