The effects of serum lipids on the <it>in vitro</it> activity of lumefantrine and atovaquone against <it>Plasmodium falciparum</it>

<p>Abstract</p> <p>Background</p> <p>Lumefantrine and atovaquone are highly lipophilic anti-malarial drugs. As a consequence absorption is increased when the drugs are taken together with a fatty meal, but the free fraction of active drug decreases in the presence of tr...

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Main Authors: Chotivanich Kesinee, Mungthin Mathirut, Ruengweerayuth Ronnatrai, Udomsangpetch Rachanee, Dondorp Arjen M, Singhasivanon Pratap, Pukrittayakamee Sasithon, White Nicholas J
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/177