Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells

The peritoneal cavity is a complicated myeloid niche containing a mixed population of resident macrophages and infiltrating cells that are responsive to inflammatory cues. Here the authors trace the fate of these infiltrating macrophages, their conversion to resident cells and how this is altered by...

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Main Authors: P. A. Louwe, L. Badiola Gomez, H. Webster, G. Perona-Wright, C. C. Bain, S. J. Forbes, S. J. Jenkins
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21778-0
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spelling doaj-33ac849202d4420a84888f070446b56d2021-03-21T12:14:58ZengNature Publishing GroupNature Communications2041-17232021-03-0112111510.1038/s41467-021-21778-0Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cellsP. A. Louwe0L. Badiola Gomez1H. Webster2G. Perona-Wright3C. C. Bain4S. J. Forbes5S. J. Jenkins6Centre for Inflammation Research, Queens Medical Research InstituteCentre for Inflammation Research, Queens Medical Research InstituteInstitute of Infection, Immunity & Inflammation, University of GlasgowInstitute of Infection, Immunity & Inflammation, University of GlasgowCentre for Inflammation Research, Queens Medical Research InstituteCentre for Regenerative Medicine, University of EdinburghCentre for Inflammation Research, Queens Medical Research InstituteThe peritoneal cavity is a complicated myeloid niche containing a mixed population of resident macrophages and infiltrating cells that are responsive to inflammatory cues. Here the authors trace the fate of these infiltrating macrophages, their conversion to resident cells and how this is altered by the local inflammatory state over time.https://doi.org/10.1038/s41467-021-21778-0
collection DOAJ
language English
format Article
sources DOAJ
author P. A. Louwe
L. Badiola Gomez
H. Webster
G. Perona-Wright
C. C. Bain
S. J. Forbes
S. J. Jenkins
spellingShingle P. A. Louwe
L. Badiola Gomez
H. Webster
G. Perona-Wright
C. C. Bain
S. J. Forbes
S. J. Jenkins
Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
Nature Communications
author_facet P. A. Louwe
L. Badiola Gomez
H. Webster
G. Perona-Wright
C. C. Bain
S. J. Forbes
S. J. Jenkins
author_sort P. A. Louwe
title Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
title_short Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
title_full Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
title_fullStr Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
title_full_unstemmed Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
title_sort recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-03-01
description The peritoneal cavity is a complicated myeloid niche containing a mixed population of resident macrophages and infiltrating cells that are responsive to inflammatory cues. Here the authors trace the fate of these infiltrating macrophages, their conversion to resident cells and how this is altered by the local inflammatory state over time.
url https://doi.org/10.1038/s41467-021-21778-0
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