Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care
Oral health is considered an important factor of general health and it contributes to the quality of life. Despite the raising awareness of preventive measures, the prevalence of oral health conditions continues to increase. In this context, a growing interest in investigating natural resources like...
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doaj-33ae2039afc74da1a737c9c6d2df8f212020-11-25T02:48:49ZengMDPI AGAntioxidants2076-39212020-06-01950250210.3390/antiox9060502Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral CareCătălina Bogdan0Anca Pop1Sonia M. Iurian2Daniela Benedec3Mirela L. Moldovan4Department of Dermopharmacy and Cosmetics, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 I. Creangă Street, 400010 Cluj-Napoca, RomaniaDepartment of Toxicology, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 6 L. Pasteur Street, 400349 Cluj-Napoca, RomaniaDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 V. Babeș Street, 400012 Cluj-Napoca, RomaniaDepartment of Pharmacognosy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 I. Creangă Street, 400010 Cluj-Napoca, RomaniaDepartment of Dermopharmacy and Cosmetics, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 I. Creangă Street, 400010 Cluj-Napoca, RomaniaOral health is considered an important factor of general health and it contributes to the quality of life. Despite the raising awareness of preventive measures, the prevalence of oral health conditions continues to increase. In this context, a growing interest in investigating natural resources like<i> Vitis vinifera (V. vinifera)</i> phenolic compounds (PhCs) as oral health promoters has emerged. This paper aims to review the evidence about the bioactivities of <i>V. vinifera</i> by-products in oral health. Up to date, a high number of studies have thoroughly reported the antimicrobial and antiplaque activity of <i>V. vinifera</i> extracts against <i>S. mutans</i> or in multi-species biofilms. Moreover, the bioactive compounds from <i>V. vinifera</i> by-products have been shown to modulate the periodontal inflammatory response and the underlying oxidative stress imbalance induced by the pathogenic bacteria. Considering these beneficial effects, the utility of V. vinifera by-products in the maintaining of oral health and the necessary steps towards the development of oral care products were emphasized. In conclusion, the high potential of <i>V. vinifera </i>by-products could be valorized in the development of oral hygiene products with multi-target actions in the prevention and progression of several oral conditions.https://www.mdpi.com/2076-3921/9/6/502Vitis viniferaby-productsoral healthantimicrobialanti-inflammatoryantioxidant |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Cătălina Bogdan Anca Pop Sonia M. Iurian Daniela Benedec Mirela L. Moldovan |
spellingShingle |
Cătălina Bogdan Anca Pop Sonia M. Iurian Daniela Benedec Mirela L. Moldovan Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care Antioxidants Vitis vinifera by-products oral health antimicrobial anti-inflammatory antioxidant |
author_facet |
Cătălina Bogdan Anca Pop Sonia M. Iurian Daniela Benedec Mirela L. Moldovan |
author_sort |
Cătălina Bogdan |
title |
Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care |
title_short |
Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care |
title_full |
Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care |
title_fullStr |
Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care |
title_full_unstemmed |
Research Advances in the Use of Bioactive Compounds from <i>Vitis vinifera</i> By-Products in Oral Care |
title_sort |
research advances in the use of bioactive compounds from <i>vitis vinifera</i> by-products in oral care |
publisher |
MDPI AG |
series |
Antioxidants |
issn |
2076-3921 |
publishDate |
2020-06-01 |
description |
Oral health is considered an important factor of general health and it contributes to the quality of life. Despite the raising awareness of preventive measures, the prevalence of oral health conditions continues to increase. In this context, a growing interest in investigating natural resources like<i> Vitis vinifera (V. vinifera)</i> phenolic compounds (PhCs) as oral health promoters has emerged. This paper aims to review the evidence about the bioactivities of <i>V. vinifera</i> by-products in oral health. Up to date, a high number of studies have thoroughly reported the antimicrobial and antiplaque activity of <i>V. vinifera</i> extracts against <i>S. mutans</i> or in multi-species biofilms. Moreover, the bioactive compounds from <i>V. vinifera</i> by-products have been shown to modulate the periodontal inflammatory response and the underlying oxidative stress imbalance induced by the pathogenic bacteria. Considering these beneficial effects, the utility of V. vinifera by-products in the maintaining of oral health and the necessary steps towards the development of oral care products were emphasized. In conclusion, the high potential of <i>V. vinifera </i>by-products could be valorized in the development of oral hygiene products with multi-target actions in the prevention and progression of several oral conditions. |
topic |
Vitis vinifera by-products oral health antimicrobial anti-inflammatory antioxidant |
url |
https://www.mdpi.com/2076-3921/9/6/502 |
work_keys_str_mv |
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