Transcriptional-Readthrough RNAs Reflect the Phenomenon of “A Gene Contains Gene(s)” or “Gene(s) within a Gene” in the Human Genome, and Thus Are Not Chimeric RNAs

Transcriptional-Readthrough RNAs Reflect the Phenomenon of “A Gene Contains Gene(s)” or “Gene(s) within a Gene” in the Human Genome, and Thus Are Not Chimeric RNAs

Tens of thousands of chimeric RNAs, i.e., RNAs with sequences of two genes, have been identified in human cells. Most of them are formed by two neighboring genes on the same chromosome and are considered to be derived via transcriptional readthrough, but a true readthrough event still awaits more ev...

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Bibliographic Details
Main Authors: Yan He, Chengfu Yuan, Lichan Chen, Mingjuan Lei, Lucas Zellmer, Hai Huang, Dezhong Joshua Liao
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Genes
Subjects:
chimeric RNA
fusion gene
transcriptional readthrough
cis-splicing
trans-splicing
reverse transcription
polymerase chain reactions
Online Access:http://www.mdpi.com/2073-4425/9/1/40

Internet

http://www.mdpi.com/2073-4425/9/1/40

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