Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus Architecture.

Foamy viruses (FV) belong to the genus Spumavirus, which forms a distinct lineage in the Retroviridae family. Although the infection in natural hosts and zoonotic transmission to humans is asymptomatic, FVs can replicate well in human cells making it an attractive gene therapy vector candidate. Here...

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Bibliographic Details
Main Authors: Grégory Effantin, Leandro F Estrozi, Nick Aschman, Patricia Renesto, Nicole Stanke, Dirk Lindemann, Guy Schoehn, Winfried Weissenhorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005721