Over-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovani.

Over-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovani.

BACKGROUND:Resistance emergence against antileishmanial drugs, particularly Sodium Antimony Gluconate (SAG) has severely hampered the therapeutic strategy against visceral leishmaniasis, the mechanism of resistance being indistinguishable. Cysteine leucine rich protein (CLrP), was recognized as one...

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Bibliographic Details
Main Authors: Sanchita Das, Priyanka Shah, Rati Tandon, Narendra Kumar Yadav, Amogh A Sahasrabuddhe, Shyam Sundar, Mohammad Imran Siddiqi, Anuradha Dube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4546639?pdf=render

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http://europepmc.org/articles/PMC4546639?pdf=render

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