The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias

The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias

Intrastriatal transplantation of fetal ventral mesencephalon (VM) tissue provides the potential to alleviate motor symptoms of Parkinson's disease (PD) and levodopa-induced dyskinesia (LID). However, the degree of recovery varies among individuals with an incidence of “off-phase”, graft-induced...

Full description

Bibliographic Details
Main Authors: Wei-Li Kuan, Rachel Lin, Pam Tyers, Roger A. Barker
Format: Article
Language:English
Published: Elsevier 2007-03-01
Series:Neurobiology of Disease
Subjects:
Neural transplantation
6-hydroxydopamine
Levodopa-induced dyskinesia
Abnormal involuntary
Movement
Girk2
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106002944

Internet

http://www.sciencedirect.com/science/article/pii/S0969996106002944

Similar Items