Differential toxicities of albendazole and its two main metabolites to Balb/c 3T3, HepG2, and FaO lines and rat hepatocytes

Differential toxicities of albendazole and its two main metabolites to Balb/c 3T3, HepG2, and FaO lines and rat hepatocytes

Introduction: The cytotoxicity of anthelmintic agent, albendazole (ABZ) and its two major metabolites, sulfoxide (ABZSO) and sulfone (ABZ-SO2), on non-hepatic Balb/c 3T3 line, two hepatoma cell lines (FaO, HepG2), and isolated rat hepatocytes was investigated. Material and Methods: Cell cultures wer...

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Bibliographic Details
Main Authors: Radko Lidia, Minta Maria, Stypuła-Trębas Sylwia
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Journal of Veterinary Research
Subjects:
albendazole
metabolites
cytotoxicity
cell cultures
Online Access:https://doi.org/10.1515/jvetres-2016-0073

Internet

https://doi.org/10.1515/jvetres-2016-0073

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