Resolution-Associated Lactoferrin Peptides Limit LPS Signaling and Cytokine Secretion from Human Macrophages

The neutrophil granule protein lactoferrin is cleaved and accumulates in efferocytic macrophages as inflammation is resolved. Two peptides present within a resolution-associated 17 kDa fragment of lactoferrin promote the termination of inflammation in vivo by enhancing murine macrophage reprogrammin...

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Bibliographic Details
Main Authors: Aviv Lutaty, Soaad Soboh, Sagie Schif-Zuck, Amiram Ariel
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
LPS
Online Access:https://www.mdpi.com/1422-0067/21/14/5166