The Plasticity of Mesenchymal Stem Cells in Regulating Surface HLA-I

Summary: A low surface expression level of human leukocyte antigen class I (HLA-I) ensures that the mesenchymal stem cells (MSCs) escape from the allogeneic recipients' immunological surveillance. Here, we discovered that both transcriptional and synthesis levels of HLA-I in MSCs increased cont...

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Bibliographic Details
Main Authors: Yafei Wang, Jiayun Huang, Lin Gong, Dongsheng Yu, Chenrui An, Varitsara Bunpetch, Jun Dai, He Huang, Xiaohui Zou, Hongwei Ouyang, Hua Liu
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301087