Metabolic Rearrangements Causing Elevated Proline and Polyhydroxybutyrate Accumulation During the Osmotic Adaptation Response of Bacillus megaterium

Metabolic Rearrangements Causing Elevated Proline and Polyhydroxybutyrate Accumulation During the Osmotic Adaptation Response of Bacillus megaterium

For many years now, Bacillus megaterium serves as a microbial workhorse for the high-level production of recombinant proteins in the g/L-scale. However, efficient and stable production processes require the knowledge of the molecular adaptation strategies of the host organism to establish optimal en...

Full description

Bibliographic Details
Main Authors: Thibault Godard, Daniela Zühlke, Georg Richter, Melanie Wall, Manfred Rohde, Katharina Riedel, Ignacio Poblete-Castro, Rainer Krull, Rebekka Biedendieck
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Bacillus megaterium
osmotic stress adaptation
transcriptomics
proteomics
flux analysis
proline
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00047/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00047/full

Similar Items