Modulation of CaV1.3b L-type calcium channels by M1 muscarinic receptors varies with CaVβ subunit expression

Modulation of CaV1.3b L-type calcium channels by M1 muscarinic receptors varies with CaVβ subunit expression

Abstract Objectives We examined whether two G protein-coupled receptors (GPCRs), muscarinic M1 receptors (M1Rs) and dopaminergic D2 receptors (D2Rs), utilize endogenously released fatty acid to inhibit L-type Ca2+ channels, CaV1.3. HEK-293 cells, stably transfected with M1Rs, were used to transientl...

Full description

Bibliographic Details
Main Authors: Mandy L. Roberts-Crowley, Ann R. Rittenhouse
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Research Notes
Subjects:
Acetylcholine
CaVβ subunit
Dopamine
L-type calcium current
Online Access:http://link.springer.com/article/10.1186/s13104-018-3783-x

Internet

http://link.springer.com/article/10.1186/s13104-018-3783-x

Similar Items