Neutrophils are essential as a source of IL-17 in the effector phase of arthritis.

Neutrophils are essential as a source of IL-17 in the effector phase of arthritis.

OBJECTIVE: Th17 has been shown to have a pivotal role in the development of arthritis. However, the role of IL-17 in the T cell-independent effector phase has not fully been examined. We investigated whether IL-17 is involved in the effector phase of arthritis by using K/BxN serum-induced arthritis...

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Main Authors: Masaki Katayama, Koichiro Ohmura, Naoichiro Yukawa, Chikashi Terao, Motomu Hashimoto, Hajime Yoshifuji, Daisuke Kawabata, Takao Fujii, Yoichiro Iwakura, Tsuneyo Mimori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646022?pdf=render

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