Purple perilla extracts allay ER stress in lipid-laden macrophages.

There is a growing body of evidence that excess lipids, hypoxic stress and other inflammatory signals can stimulate endoplasmic reticulum (ER) stress in metabolic diseases. However, the pathophysiological importance and the underlying mechanisms of this phenomenon remain unknown. The current study i...

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Bibliographic Details
Main Authors: Sin-Hye Park, Daekeun Shin, Soon Sung Lim, Jae-Yong Lee, Young-Hee Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4198214?pdf=render