Synthesis and Biological Activity of Peptide Derivatives of Iodoquinazolinones/Nitroimidazoles

Synthesis and Biological Activity of Peptide Derivatives of Iodoquinazolinones/Nitroimidazoles

Two substituted quinazolinyl/imidazolyl-salicylic acids 5, 6 were synthesized bythe reaction of 6-iodo-2-methylbenzoxazin-4-one/5-nitroimidazole with 5-aminosalicylicacid (5-ASA). Coupling of compounds 5 and 6 with different amino acid esterhydrochlorides, dipeptide and tripeptide methyl esters yiel...

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Bibliographic Details
Main Authors: Rakesh Yadav, Anil Kumar, Rajiv Dahiya
Format: Article
Language:English
Published: MDPI AG 2008-04-01
Series:Molecules
Subjects:
Quinazolinone
imidazole
5-aminosalicylic acid
peptides
antimicrobial activity
anthelmintic activity.
Online Access:http://www.mdpi.com/1420-3049/13/4/958/

Internet

http://www.mdpi.com/1420-3049/13/4/958/

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