A longitudinal analysis of brain extracellular free water in HIV infected individuals

Abstract Initiation of combination antiretroviral therapy (cART) reduces inflammation in HIV-infected (HIV+) individuals. Recent studies demonstrated that diffusion MRI based extracellular free water (FW) modeling can be sensitive to neuroinflammation. Here, we investigate the FW in HIV-infection, i...

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Bibliographic Details
Main Authors: Md Nasir Uddin, Abrar Faiyaz, Lu Wang, Yuchuan Zhuang, Kyle D. Murray, Maxime Descoteaux, Madalina E. Tivarus, Miriam T. Weber, Jianhui Zhong, Xing Qiu, Giovanni Schifitto
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87801-y