Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis

Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis

Superoxide dismutase 1 (SOD1) is an antioxidant enzyme that converts superoxide anion radicals into hydrogen peroxide and molecular oxygen. The senescence marker protein-30 (SMP30) is a gluconolactonase that functions as an antioxidant protein in mammals due to its involvement in ascorbic acid (AA)...

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Bibliographic Details
Main Authors: Yoshitaka Kondo, Hirofumi Masutomi, Yoshihiro Noda, Yusuke Ozawa, Keita Takahashi, Setsuko Handa, Naoki Maruyama, Takahiko Shimizu, Akihito Ishigami
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Ascorbic acid
Non-alcoholic fatty liver disease
Reactive oxygen species
SMP30
SOD1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000515

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http://www.sciencedirect.com/science/article/pii/S2211546314000515

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