Thermoreversible hyaluronan-hydrogel and autologous nucleus pulposus cell delivery regenerates human intervertebral discs in an ex vivo, physiological organ culture model

Thermoreversible hyaluronan-hydrogel and autologous nucleus pulposus cell delivery regenerates human intervertebral discs in an ex vivo, physiological organ culture model

Numerous studies show promise for cell-based tissue engineering strategies aiming to repair painful intervertebral disc (IVD) degeneration. However, clinical translation to human IVD repair is slow. In the present study, the regenerative potential of an autologous nucleus pulposus (NP)-cell-seeded t...

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Bibliographic Details
Main Authors: DH Rosenzweig, R Fairag, AP Mathieu, L Li, , ,, ,, D Eglin, M D’Este, T Steffen, MH Weber, JA Ouellet, L Haglund
Format: Article
Language:English
Published: AO Research Institute Davos 2018-10-01
Series:European Cells & Materials
Subjects:
Hydrogel
T1ρ magnetic resonance imaging
human intervertebral disc
bioreactors
tissue engineering
nucleus pulposus
autologous cell implantation.
Online Access:http://www.ecmjournal.org/papers/vol036/pdf/v036a15.pdf

Internet

http://www.ecmjournal.org/papers/vol036/pdf/v036a15.pdf

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