NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.

NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.

Nuclear factor (NF)-kappaB is a major survival pathway engaged by the Human T-Lymphotropic Virus type 1 (HTLV-1) Tax protein. Tax1 activation of NF-kappaB occurs predominantly in the cytoplasm, where Tax1 binds NF-kappaB Essential Modulator (NEMO/IKKgamma) and triggers the activation of IkappaB kina...

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Bibliographic Details
Main Authors: Chloé Journo, Josina Filipe, Frédégonde About, Sébastien A Chevalier, Philippe V Afonso, John N Brady, David Flynn, Frédéric Tangy, Alain Israël, Pierre-Olivier Vidalain, Renaud Mahieux, Robert Weil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19609363/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19609363/?tool=EBI

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