Free cysteine modulates the conformation of human C/EBP homologous protein.

Free cysteine modulates the conformation of human C/EBP homologous protein.

The C/EBP Homologous Protein (CHOP) is a nuclear protein that is integral to the unfolded protein response culminating from endoplasmic reticulum stress. Previously, CHOP was shown to comprise extensive disordered regions and to self-associate in solution. In the current study, the intrinsically dis...

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Bibliographic Details
Main Authors: Vinay K Singh, Mona N Rahman, Kim Munro, Vladimir N Uversky, Steven P Smith, Zongchao Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3319616?pdf=render

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http://europepmc.org/articles/PMC3319616?pdf=render

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