Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma

Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma

Abstract Background A challenge in the post-GWAS era is to assign function to disease-associated variants. However, available resources do not include all tissues or environmental exposures that are relevant to all diseases. For example, exaggerated bronchoconstriction of airway smooth muscle cells...

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Bibliographic Details
Main Authors: Emma E. Thompson, Quynh Dang, Blair Mitchell-Handley, Kavitha Rajendran, Sumati Ram-Mohan, Julian Solway, Carole Ober, Ramaswamy Krishnan
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Genome Medicine
Subjects:
Asthma
Epigenetics
Differential expression
Cases
Controls
Online Access:http://link.springer.com/article/10.1186/s13073-020-00759-w

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http://link.springer.com/article/10.1186/s13073-020-00759-w

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