Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application
Cosmetics has recently focused on biobased skin-compatible materials. Materials from natural sources can be used to produce more sustainable skin contact products with enhanced bioactivity. Surface functionalization using natural-based nano/microparticles is thus a subject of study, aimed at better...
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doaj-3751be8d74d14c20a6984fc51f9311f12021-07-23T13:56:58ZengMDPI AGMolecules1420-30492021-07-01264374437410.3390/molecules26144374Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact ApplicationBahareh Azimi0Claudio Ricci1Alessandra Fusco2Lorenzo Zavagna3Stefano Linari4Giovanna Donnarumma5Ahdi Hadrich6Patrizia Cinelli7Maria-Beatrice Coltelli8Serena Danti9Andrea Lazzeri10Interuniversity National Consortiums of Materials Science and Technology (INSTM), 50121 Firenze, ItalyInteruniversity National Consortiums of Materials Science and Technology (INSTM), 50121 Firenze, ItalyDepartment of Experimental Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyInteruniversity National Consortiums of Materials Science and Technology (INSTM), 50121 Firenze, ItalyLinari Engineering s.r.l., 56121 Pisa, ItalyDepartment of Experimental Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyBiomass Valorization Platform-Materials, Celabor s.c.r.l., 4650 Chaineux, BelgiumInteruniversity National Consortiums of Materials Science and Technology (INSTM), 50121 Firenze, ItalyInteruniversity National Consortiums of Materials Science and Technology (INSTM), 50121 Firenze, ItalyInteruniversity National Consortiums of Materials Science and Technology (INSTM), 50121 Firenze, ItalyDepartment of Civil and Industrial Engineering, University of Pisa, 56126 Pisa, ItalyCosmetics has recently focused on biobased skin-compatible materials. Materials from natural sources can be used to produce more sustainable skin contact products with enhanced bioactivity. Surface functionalization using natural-based nano/microparticles is thus a subject of study, aimed at better understanding the skin compatibility of many biopolymers also deriving from biowaste. This research investigated electrospray as a method for surface modification of cellulose tissues with chitin nanofibrils (CNs) using two different sources—namely, vegetable (i.e., from fungi), and animal (from crustaceans)—and different solvent systems to obtain a biobased and skin-compatible product. The surface of cellulose tissues was uniformly decorated with electrosprayed CNs. Biological analysis revealed that all treated samples were suitable for skin applications since human dermal keratinocytes (i.e., HaCaT cells) successfully adhered to the processed tissues and were viable after being in contact with released substances in culture media. These results indicate that the use of solvents did not affect the final cytocompatibility due to their effective evaporation during the electrospray process. Such treatments did not also affect the characteristics of cellulose; in addition, they showed promising anti-inflammatory and indirect antimicrobial activity toward dermal keratinocytes in vitro. Specifically, cellulosic substrates decorated with nanochitins from shrimp showed strong immunomodulatory activity by first upregulating then downregulating the pro-inflammatory cytokines, whereas nanochitins from mushrooms displayed an overall anti-inflammatory activity via a slight decrement of the pro-inflammatory cytokines and increment of the anti-inflammatory marker. Electrospray could represent a green method for surface modification of sustainable and biofunctional skincare products.https://www.mdpi.com/1420-3049/26/14/4374surface functionalizationchitin nanofibrilcelluloseskincareanti-inflammatorybiobased |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bahareh Azimi Claudio Ricci Alessandra Fusco Lorenzo Zavagna Stefano Linari Giovanna Donnarumma Ahdi Hadrich Patrizia Cinelli Maria-Beatrice Coltelli Serena Danti Andrea Lazzeri |
spellingShingle |
Bahareh Azimi Claudio Ricci Alessandra Fusco Lorenzo Zavagna Stefano Linari Giovanna Donnarumma Ahdi Hadrich Patrizia Cinelli Maria-Beatrice Coltelli Serena Danti Andrea Lazzeri Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application Molecules surface functionalization chitin nanofibril cellulose skincare anti-inflammatory biobased |
author_facet |
Bahareh Azimi Claudio Ricci Alessandra Fusco Lorenzo Zavagna Stefano Linari Giovanna Donnarumma Ahdi Hadrich Patrizia Cinelli Maria-Beatrice Coltelli Serena Danti Andrea Lazzeri |
author_sort |
Bahareh Azimi |
title |
Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application |
title_short |
Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application |
title_full |
Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application |
title_fullStr |
Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application |
title_full_unstemmed |
Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application |
title_sort |
electrosprayed shrimp and mushroom nanochitins on cellulose tissue for skin contact application |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2021-07-01 |
description |
Cosmetics has recently focused on biobased skin-compatible materials. Materials from natural sources can be used to produce more sustainable skin contact products with enhanced bioactivity. Surface functionalization using natural-based nano/microparticles is thus a subject of study, aimed at better understanding the skin compatibility of many biopolymers also deriving from biowaste. This research investigated electrospray as a method for surface modification of cellulose tissues with chitin nanofibrils (CNs) using two different sources—namely, vegetable (i.e., from fungi), and animal (from crustaceans)—and different solvent systems to obtain a biobased and skin-compatible product. The surface of cellulose tissues was uniformly decorated with electrosprayed CNs. Biological analysis revealed that all treated samples were suitable for skin applications since human dermal keratinocytes (i.e., HaCaT cells) successfully adhered to the processed tissues and were viable after being in contact with released substances in culture media. These results indicate that the use of solvents did not affect the final cytocompatibility due to their effective evaporation during the electrospray process. Such treatments did not also affect the characteristics of cellulose; in addition, they showed promising anti-inflammatory and indirect antimicrobial activity toward dermal keratinocytes in vitro. Specifically, cellulosic substrates decorated with nanochitins from shrimp showed strong immunomodulatory activity by first upregulating then downregulating the pro-inflammatory cytokines, whereas nanochitins from mushrooms displayed an overall anti-inflammatory activity via a slight decrement of the pro-inflammatory cytokines and increment of the anti-inflammatory marker. Electrospray could represent a green method for surface modification of sustainable and biofunctional skincare products. |
topic |
surface functionalization chitin nanofibril cellulose skincare anti-inflammatory biobased |
url |
https://www.mdpi.com/1420-3049/26/14/4374 |
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