Most published meta-regression analyses based on aggregate data suffer from methodological pitfalls: a meta-epidemiological study

Abstract Background Due to clinical and methodological diversity, clinical studies included in meta-analyses often differ in ways that lead to differences in treatment effects across studies. Meta-regression analysis is generally recommended to explore associations between study-level characteristic...

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Bibliographic Details
Main Authors: Michael Geissbühler, Cesar A. Hincapié, Soheila Aghlmandi, Marcel Zwahlen, Peter Jüni, Bruno R. da Costa
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-021-01310-0