HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes

HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes

Cell-cell interactions are crucial for organ development and function. In the heart, endothelial cells engage in bidirectional communication with cardiomyocytes regulating cardiac development and growth. We aimed to elucidate the organotypic development of cardiac endothelial cells and cardiomyocyte...

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Bibliographic Details
Main Authors: Emmi Helle, Minna Ampuja, Alexandra Dainis, Laura Antola, Elina Temmes, Erik Tolvanen, Eero Mervaala, Riikka Kivelä
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human induced pluripotent stem cells
cardiomyocytes
endothelial cells
co-culture
single cell RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.715093/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.715093/full

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