The Role of Brain-Derived Neurotrophic Factor in Irritable Bowel Syndrome

Several studies have implied a role of brain-derived neurotrophic factor (BDNF) in abdominal pain modulation in irritable bowel syndrome (IBS). The aim of this study was to establish BDNF protein expression in human colonic biopsies and to show variation in IBS compared to controls. BDNF protein and...

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Bibliographic Details
Main Authors: Thomas Jan Konturek, Cristina Martinez, Beate Niesler, Ivo van der Voort, Hubert Mönnikes, Andreas Stengel, Miriam Goebel-Stengel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2020.531385/full