Efficient Transduction and Expansion of Ovine Macrophages for Gene Therapy Implementations

Efficient Transduction and Expansion of Ovine Macrophages for Gene Therapy Implementations

A number of bacteria provoking zoonotic diseases present intracellular survival and a host cell tropism limited to the monocyte/macrophage lineage. Thus, infection is rendered difficult to eradicate, causing chronic inflammatory reactions to the host and widespread prevalence. Although self-inactiva...

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Bibliographic Details
Main Authors: Garyfalia Karponi, Spyridon Kritas, Evanthia Petridou, Eleni Papanikolaou
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Veterinary Sciences
Subjects:
zoonotic diseases
macrophages
ruminant animals
lentiviral vectors
transduction
gene therapy
Online Access:http://www.mdpi.com/2306-7381/5/2/57

Internet

http://www.mdpi.com/2306-7381/5/2/57

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