Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation

Summary: Loss of functional cardiomyocytes is a major determinant of heart failure after myocardial infarction. Previous high throughput screening studies have identified a few microRNAs (miRNAs) that can induce cardiomyocyte proliferation and stimulate cardiac regeneration in mice. Here, we show th...

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Bibliographic Details
Main Authors: Consuelo Torrini, Ryan John Cubero, Ellen Dirkx, Luca Braga, Hashim Ali, Giulia Prosdocimo, Maria Ines Gutierrez, Chiara Collesi, Danilo Licastro, Lorena Zentilin, Miguel Mano, Serena Zacchigna, Michele Vendruscolo, Matteo Marsili, Areejit Samal, Mauro Giacca
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719306163