Enhancing the secretion pathway maximizes the effects of mixed feeding strategy for glucose oxidase production in the methylotrophic yeast Pichia pastoris

Abstract Background A mixed feeding strategy (co-feeding of complex carbon sources with methanol) has become a common practice for process development in Pichia pastoris to increase cell biomass and enzyme production levels. However, in some cases mixed feeding did not have a significant impact or e...

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Bibliographic Details
Main Authors: Olufemi Emmanuel Bankefa, Meiyu Wang, Taicheng Zhu, Yin Li
Format: Article
Language:English
Published: SpringerOpen 2018-05-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40643-018-0211-y