Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet

Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a dramatic reprogramming of the liver transcript...

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Bibliographic Details
Main Authors: Yufeng Qin, Sara A. Grimm, John D. Roberts, Kaliopi Chrysovergis, Paul A. Wade
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14796-x