The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines

Background: P300 is a member of the mammalian histone acetyl transferase (HAT) family, an enzyme that acetylates histones and several non-histone proteins including P53 (the most important tumor suppressor gene) during stress, which plays an important role in the apoptosis of tumor cells. Hereby, th...

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Bibliographic Details
Main Authors: Mehdi Nikbakht Dastjerdi, Mohammad R Salahshoor, Mohammad Mardani, Batool Hashemibeni, Shiva Roshankhah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Advanced Biomedical Research
Subjects:
P53
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2013;volume=2;issue=1;spage=24;epage=24;aulast=Dastjerdi