Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective

The tumor microenvironment (TME) comprises complex interactions of multiple cell types that determines cell behavior and metabolism such as nutrient competition and immune suppression. We discuss the various types of heterogeneity that exist in solid tumors, and the complications this invokes for st...

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Bibliographic Details
Main Authors: Teresa W.-M. Fan, Richard M. Higashi, Yelena Chernayavskaya, Andrew N. Lane
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/10/6/249